When are randomized trials unnecessary? A signal detection theory approach to approving new treatments based on non‐randomized studies
نویسندگان
چکیده
منابع مشابه
New treatments compared to established treatments in randomized trials.
BACKGROUND The proportion of proposed new treatments that are 'successful' is of ethical, scientific, and public importance. We investigated how often new, experimental treatments evaluated in randomized controlled trials (RCTs) are superior to established treatments. OBJECTIVES Our main question was: "On average how often are new treatments more effective, equally effective or less effective...
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ژورنال
عنوان ژورنال: Journal of Evaluation in Clinical Practice
سال: 2020
ISSN: 1356-1294,1365-2753
DOI: 10.1111/jep.13497